Alfredo A. Sadun, MD, PhD

Alfredo A. Sadun, MD, PhD
Flora L. Thornton Chair
Professor of Ophthalmology and Neurological Surgery
Doheny Eye Institute
Keck School of Medicine at USC

Dr. Sadun earned an M.D. and a Ph.D. in neuroanatomy from Albert Einstein College of Medicine. He completed a residency and chief residency at the Massachusetts Eye & Ear Infirmary, Harvard Medical School. He completed a combined clinical fellowship in neuro-ophthalmology at Boston University School of Medicine and Harvard Medical School. Dr. Sadun and a team of researchers at the Doheny Eye Institute pioneered research in optic nerve dysfunction in patients with Alzheimer's disease. His research and clinical expertise in diseases of the optic nerve made him the choice to lead a team of investigators that determined the metabolic cause of an epidemic of optic neuropathy in Cuba, 1993-1994. Dr. Sadun is a Professor of Ophthalmology and Neurological Surgery at the USC Keck School of Medicine.

Research Interests

  • Diseases of the Optic Nerve
  • Optic Nerve Regeneration
  • Neuro-Protection
  • Diseases of Mitochondrial Impairment

Clinical Interests

  • Neuro-Ophthalmology
  • Optic Neuropathies
  • Orbital Disease
  • Muscle Surgery



  • Albert Einstein College of Medicine, Ph.D., 1976
  • Albert Einstein College of Medicine, M.D., 1978
  • Massachusetts Institute of Technology (MIT), B.Sc., 1972


  • Huntington Memorial Hospital, Pasadena, CA, 1978 - 1979


  • Mass. Eye & Ear Infirmary, Harvard Medical School, Boston, MA, 1979 - 1982


  • Massachusetts Eye & Ear Infirmary, 1982 - 1983

Board Certification

  • American Board of Ophthalmology, 1983


  • Lighthouse International (Pizart) Lifetime Achievement, 1999
  • Best Doctors in America for Both Ophthalmology and Neurology, 1994
  • American Academy of Ophthalmology Honor Award, 1993



  • North American Neuro-Ophthalmological Society (NANOS)
  • AUPO Program Director's Advisory Council
  • Association for Research in Vision Organization (ARVO)

Clinical Affiliation

  • USC Keck School of Medicine
  • Doheny Eye Institute
  • LA County Hospital
  • Norris Cancer Hospital